Article
Genetic susceptibility to Hodgkin's lymphoma associated with the human leukocyte antigen region.
European journal of haematology. Supplementum - 1 Jul 2005
Diepstra A, Niens M, te Meerman G J, Poppema S, van den Berg A
Abstract excerpt
Based on the presence of an abundant inflammatory infiltrate, expression of a broad spectrum of cytokines and the professional antigen presenting phenotype of Hodgkin Reed-Sternberg cells it can be anticipated that immunological mechanisms play a major role in the pathogenesis of Hodgkin's lymphoma (HL). Genetic susceptibility to HL probably relates to functionality of the immune system and the large number of...
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