Article
Estimating local ancestry in admixed populations.
American journal of human genetics - 1 Feb 2008
Sankararaman Sriram, Sridhar Srinath, Kimmel Gad, Halperin Eran
Abstract excerpt
Large-scale genotyping of SNPs has shown a great promise in identifying markers that could be linked to diseases. One of the major obstacles involved in performing these studies is that the underlying population substructure could produce spurious associations. Population substructure can be caused by the presence of two distinct subpopulations or a single pool of admixed individuals. In this work, we focus on...
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