Article
Local Ancestry Inference in Large Pedigrees.
Scientific reports - 13 Jan 2020
Wang Heming, Sofer Tamar, Zhang Xiang, Elston Robert C, Redline Susan, Zhu Xiaofeng
Abstract excerpt
Local ancestry, defined as the genetic ancestry at a genomic location of an admixed individual, is widely used as a genetic marker in genetic association and evolutionary genetics studies. Many methods have been developed to infer the local ancestries in a set of unrelated individuals, a few of them have been extended to small nuclear families, but none can be applied to large (e.g. three-generation) pedigrees....
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