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Article

IL-13-mediated gender difference in susceptibility to autoimmune encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2008

Sinha Sushmita, Kaler Laurie J, Proctor Thomas M, Teuscher Cory, Vandenbark Arthur A, Offner Halina

Abstract excerpt

Females tend to have stronger Th1-mediated immune responses and are more prone to develop autoimmune diseases, including multiple sclerosis. Macrophages are major effector cells capable of mediating or modulating immune responses in experimental autoimmune encephalomyelitis (EAE). IL-13 and estrogen have opposing roles on macrophages (the former enhancing and the latter inhibiting) in terms of MHC class II (MHC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18250480
DOI: 10.4049/jimmunol.180.4.2679
PMCID: PMC2651815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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