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Investigating the Effects of Sex Hormones on Macrophage Polarization

12 Jan 2024

Abstract excerpt

Sex differences in the development and progression of cardiovascular disease are well established, but the effects of sex hormones on macrophage polarization and pro-atherogenic functions are not well described. We hypothesize that sex hormones directly modulate macrophage polarization, and thereby regulate the progression of atherosclerosis. Bone marrow-derived monocytes from adult male and female C57BL/6 mice...

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PMID: 38256027
DOI: 10.3390/ijms25020951

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