Article
Homology modeling of breast cancer resistance protein (ABCG2).
Journal of structural biology - 1 Apr 2008
Hazai Eszter, Bikádi Zsolt
Abstract excerpt
BCRP (also known as ABCG2, MXR, and ABC-P) is a member of the ABC family that transports a wide variety of substrates. BCRP is known to play a key role as a xenobiotic transporter. Since discovering its role in multidrug resistance, considerable efforts have been made in order to gain deeper understanding of BCRP structure and function. The recent study was aimed at predicting BCRP structure by creating a...
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