Antibody to epitope tag induces internalization of human muscarinic subtype 1 receptor.

doi:10.1046/j.1471-4159.1998.70010113.x

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Article

Antibody to epitope tag induces internalization of human muscarinic subtype 1 receptor.

Journal of neurochemistry - 1 Jan 1998

Tolbert L M, Lameh J

Abstract excerpt

We have studied the effect of an antibody against the epitope EYMPME on the internalization of the human muscarinic cholinergic receptor hm1 tagged with the epitope at the amino terminus. The antibody to the tag induces internalization of the hm1 receptor within minutes after exposure of human em...

Topics

Antibodies
Cell Line
Endocytosis
Epitopes
Humans
Microscopy, Confocal
Mutation
Peptide Fragments
Receptors, Muscarinic
Second Messenger Systems
Sequence Tagged Sites

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