Article
The oligomeric nature of the murine Fc epsilon RII/CD23. Implications for function.
Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 1993
Dierks S E, Bartlett W C, Edmeades R L, Gould H J, Rao M, Conrad D H
Abstract excerpt
The low affinity receptor for IgE (Fc epsilon RII/CD23) is a type II integral membrane protein with an extracellular C-terminal region homologous to C-type animal lectins. Immediately adjacent to this lectin homology region is a sequence that is predicted to form an alpha-helical coiled-coil stalk leading to dimer or trimer formation. This provides an explanation for the known self-associative capacity for the Fc...
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