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Article

Penicillin-binding proteins and beta-lactam resistance.

FEMS microbiology reviews - 1 Mar 2008

Zapun André, Contreras-Martel Carlos, Vernet Thierry

Abstract excerpt

A number of ways and means have evolved to provide resistance to eubacteria challenged by beta-lactams. This review is focused on pathogens that resist by expressing low-affinity targets for these antibiotics, the penicillin-binding proteins (PBPs). Even within this narrow focus, a great variety of strategies have been uncovered such as the acquisition of an additional low-affinity PBP, the overexpression of an...

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Identifiers

PMID: 18248419
DOI: 10.1111/j.1574-6976.2007.00095.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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