Article
Penicillin-binding proteins and the antibacterial effectiveness of beta-lactam antibiotics.
Reviews of infectious diseases - 1 Jan 2000
Tomasz A
Abstract excerpt
It is currently believed that both the antibacterial potency and the nature of the antibacterial effects of beta-lactam antibiotics are ultimately dependent on the inhibition (acylation) of one or more of the bacterial penicillin-binding proteins (PBPs). Nevertheless, bacterial factors (e.g., aut...
Topics
- Anti-Bacterial Agents
- Bacteria
- Bacterial Proteins
- Carboxypeptidases
- Carrier Proteins
- Drug Resistance, Microbial
- Escherichia coli
- Haemophilus influenzae
- Hexosyltransferases
- Humans
- Muramoylpentapeptide Carboxypeptidase
- Mutation
- Neisseria gonorrhoeae
- Penicillin Resistance
- Penicillin-Binding Proteins
- Peptidyl Transferases
- Staphylococcus aureus
- Streptococcus pneumoniae