Article
Relaxed functional constraints on triplicate α-globin gene in the bank vole suggest a different evolutionary history from other rodents.
Heredity - 1 Jul 2014
Marková S, Searle J B, Kotlík P
Abstract excerpt
Gene duplication plays an important role in the origin of evolutionary novelties, but the mechanisms responsible for the retention and functional divergence of the duplicated copy are not fully understood. The α-globin genes provide an example of a gene family with different numbers of gene duplicates among rodents. Whereas Rattus and Peromyscus each have three adult α-globin genes (HBA-T1, HBA-T2 and HBA-T3),...
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