Article
DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans.
Genetics - 1 Feb 2008
Miyata Sachiko, Begun Jakob, Troemel Emily R, Ausubel Frederick M
Abstract excerpt
To further understand how the nematode Caenorhabditis elegans defends itself against pathogen attack, we analyzed enhanced pathogen resistance (epr) mutants obtained from a forward genetic screen. We also examined several well-characterized sterile mutants that exhibit an Epr phenotype. We found that sterility and pathogen resistance are highly correlated and that resistance in both epr and sterile mutants is...
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