Article
Variation at the cholesteryl ester transfer protein gene in relation to plasma high density lipoproteins cholesterol levels and carotid intima-media thickness.
European journal of clinical investigation - 1 Jul 2001
Kakko S, Tamminen M, Päivänsalo M, Kauma H, Rantala A O, Lilja M, Reunanen A, Kesäniemi Y A, Savolainen M J
Abstract excerpt
BACKGROUND: Cholesteryl ester transfer protein (CETP) plays a major role in lipoprotein metabolism. We have screened the CETP gene for mutations and polymorphisms regulating high density lipoproteins cholesterol (HDL-C) levels and the development of atherosclerosis, and found some polymorphisms (I405V and R451Q) to have minor effects. DESIGN: The purpose of this study was to investigate the combined effect of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.