Article
Lack of mutagenic and toxic effects of low dose potassium bromate on kidneys in the Big Blue rat.
Mutation research - 29 Mar 2008
Yamaguchi Takashi, Wei Min, Hagihara Natsuko, Omori Masako, Wanibuchi Hideki, Fukushima Shoji
Abstract excerpt
Potassium bromate (KBrO3) has been classified as a genotoxic carcinogen based on positive results in the Ames test, and chromosome aberration and micronucleus tests. The purpose of the present study was to investigate the dose-response relationship for in vivo mutagenic and toxic effects of KBrO3 in the kidneys of Big Blue rats. In experiment 1, male Big Blue rats were divided into 8 groups. KBrO3 was dissolved...
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