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Article

Megaintestine in claudin-15-deficient mice.

Gastroenterology - 1 Feb 2008

Tamura Atsushi, Kitano Yuka, Hata Masaki, Katsuno Tatsuya, Moriwaki Kazumasa, Sasaki Hiroyuki, Hayashi Hisayoshi, Suzuki Yuichi, Noda Tetsuo, Furuse Mikio, Tsukita Shoichiro, Tsukita Sachiko

Abstract excerpt

BACKGROUND & AIMS: Claudins, the major components of tight junction (TJ) strands, which form paracellular barriers, consist of 24 family members, the combination of which determines the properties of TJ-based paracellular barriers. Here, we generated claudin-15-deficient (Cldn15(-/-)) mice to examine the ubiquitously expressed functions of claudin-15. METHODS: We generated Cldn15(-/-) mice by the conventional...

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Source

Identifiers

PMID: 18242218
DOI: 10.1053/j.gastro.2007.11.040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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