Article
Loss of claudins 2 and 15 from mice causes defects in paracellular Na+ flow and nutrient transport in gut and leads to death from malnutrition.
Gastroenterology - 1 Feb 2013
Wada Masami, Tamura Atsushi, Takahashi Nobuyuki, Tsukita Sachiko
Abstract excerpt
BACKGROUND & AIMS: The intestinal symport system moves nutrients across membranes via transporters, and is required for absorption of major nutrients such as glucose, amino acids, and bile acids (which are required for fat absorption). Most of these transporters are regulated by Na(+), but the st...
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