Article
Increased expression of the glioma-associated antigen ARF4L after loss of the tumor suppressor PTEN. Laboratory investigation.
Journal of neurosurgery - 1 Feb 2008
Chi John H, Panner Amith, Cachola Kristine, Crane Courtney A, Murray Joseph, Pieper Russell O, James C David, Parsa Andrew T
Abstract excerpt
OBJECT: Despite recent advances in cancer immunotherapy, cellular mechanisms controlling expression of tumor-associated antigens are poorly understood. Mutations in cancer cells, such as loss of PTEN, may increase expression of tumor-associated antigens. The authors investigated the relationship between PTEN status and the expression of a glioma-associated antigen, adenosine diphosphate-ribosylation factor 4-like...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
