Article
Virological response to salvage therapy in HIV-infected persons carrying the reverse transcriptase K65R mutation.
Antiviral therapy - 1 Jan 2007
Antinori Andrea, Trotta Maria Paola, Lorenzini Patrizia, Torti Carlo, Gianotti Nicola, Maggiolo Franco, Ceccherini-Silberstein Francesca, Nasto Paola, Castagna Antonella, De Luca Andrea, Mussini Cristina, Andreoni Massimo, Perno Carlo Federico
Abstract excerpt
BACKGROUND: The effect of the HIV reverse transcriptase K65R mutation on virological response to salvage therapy has not been clearly defined. METHODS: From six Italian clinical centres, all consecutive patients starting salvage antiretroviral therapy after virological failure in the presence of the K65R mutation identified by a genotypic resistance test were selected. RESULTS: Among 145 subjects included over a...
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