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Article

Mutation analysis of the EGFR-NRAS-BRAF pathway in melanomas from black Africans and other subgroups of cutaneous melanoma.

Melanoma research - 1 Feb 2008

Akslen Lars A, Puntervoll Hanne, Bachmann Ingeborg M, Straume Oddbjørn, Vuhahula Edda, Kumar Rajiv, Molven Anders

Abstract excerpt

Earlier studies have shown frequent mutations in the BRAF and NRAS genes in cutaneous melanoma, but these alterations have not been examined in the rare category of melanoma from black Africans. Moreover, the frequency of epidermal growth factor receptor (EGFR) mutations in melanocytic tumors is...

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Source

Identifiers

PMID: 18227705
DOI: 10.1097/CMR.0b013e3282f32517

Genes

NRAS
BRAF
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18227705-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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