Article
Prevalence of BRAF and NRAS mutations in cutaneous melanoma patients in Taiwan.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Feb 2016
Sheen Yi-Shuan, Liao Yi-Hua, Liau Jau-Yu, Lin Ming-Hsien, Hsieh Yi-Chun, Jee Shiou-Hwa, Chu Chia-Yu
Abstract excerpt
BACKGROUND/PURPOSE: BRAF and NRAS mutations have been described in melanomas among Caucasians and some Asian populations. However, few large-scale studies have investigated the status and clinical significance of BRAF and NRAS mutations in a Taiwanese population. METHODS: Melanoma samples (n = 119) were analyzed for mutations in exons 11 and 15 of the BRAF gene, and in exons 1 and 2 of the NRAS gene. The samples...
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