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Article

Piroxicam increases colon tumorigenesis and promotes apoptosis in Mlh1 +/- /Apc1638(N/+) mice.

Anticancer research - 1 Jan 2000

Palmerini Emanuela, Fan Kunhua, Yang Kan, Risio Mauro, Edelmann Winfried, Lipkin Martin, Biasco Guido

Abstract excerpt

BACKGROUND: The present study examines the effect of piroxicam, a non-steroidal anti-inflammatory drug, on tumor development in Mlh1+/- /Apc1638(N/+) mice, in a preclinical model of human colon cancer. MATERIALS AND METHODS: Mice were fed AIN-76A diet alone or premixed with piroxicam (60 ppm) for...

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Identifiers

PMID: 18225536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18225536-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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