Article
Functional analysis of a BarX homologue (SngA) as a pleiotropic regulator in Streptomyces natalensis.
Archives of microbiology - 1 Jun 2008
Lee Kang-Mu, Lee Chang-Kwon, Choi Sun-Uk, Park Hae-Ryong, Hwang Yong-Il
Abstract excerpt
The prior sequencing of the upstream region of the gamma-butyrolactone autoregulator receptor gene (sngR) in Streptomyces natalensis revealed the presence of a 972-bp gene encoding a BarX homologue (SngA), which acts as a pleiotropic regulator controlling secondary metabolism and morphological differentiation. In this study, we investigated the in vivo function of SngA in S. natalensis, by comparing the natamycin...
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