Article
Data-mining methods as useful tools for predicting individual drug response: application to CYP2D6 data.
Human heredity - 1 Jan 2006
Sabbagh Audrey, Darlu Pierre
Abstract excerpt
OBJECTIVES: Selecting a maximally informative subset of polymorphisms to predict a clinical outcome, such as drug response, requires appropriate search methods due to the increased dimensionality associated with looking at multiple genotypes. In this study, we investigated the ability of several pattern recognition methods to identify the most informative markers in the CYP2D6 gene for the prediction of CYP2D6...
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