Article
Pattern-recognition techniques with haplotype analysis in pharmacogenomics.
Pharmacogenomics - 1 Jan 2007
Lin Eugene, Hwang Yuchi, Liang Kung-Hao, Chen Ellson Y
Abstract excerpt
Single nucleotide polymorphisms (SNPs) can be used in clinical association studies to determine the contribution of genes to drug efficacy. However, it would be extremely inefficient to test all the 10 million common SNPs for an association study. Here we review haplotype analysis and pattern-recognition techniques to systematically select candidate SNPs for candidate-gene association studies in pharmacogenomics....
Topics
- Animals
- Genetic Markers
- Haplotypes
- Humans
- Linkage Disequilibrium
- Pattern Recognition, Automated
- Pharmacogenetics
- Polymorphism, Single Nucleotide
