Article
Meta-analysis of 23 type 2 diabetes linkage studies from the International Type 2 Diabetes Linkage Analysis Consortium.
Human heredity - 1 Jan 2008
Guan Weihua, Pluzhnikov Anna, Cox Nancy J, Boehnke Michael
Abstract excerpt
BACKGROUND: The International Type 2 Diabetes Linkage Analysis Consortium was formed to localize type 2 diabetes predisposing variants based on 23 autosomal linkage scans. METHODS: We carried out meta-analysis using the genome scan meta-analysis (GSMA) method which divides the genome into bins of approximately 30 cM, ranks the best linkage results in each bin for each sample, and then sums the ranks across...
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