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Article

The LOXL1 gene variations are not associated with primary open-angle and primary angle-closure glaucomas.

Investigative ophthalmology & visual science - 1 Jun 2008

Chakrabarti Subhabrata, Rao Kollu Nageswara, Kaur Inderjeet, Parikh Rajul S, Mandal Anil K, Chandrasekhar Garudadri, Thomas Ravi

Abstract excerpt

PURPOSE: Glaucoma is a complex disease involving multiple genetic factors. Recently, single nucleotide polymorphisms (SNPs) in the LOXL1 gene have been implicated in exfoliation syndrome (XFS) and exfoliation glaucoma (XFG) but not in the primary glaucomas. This study was conducted to determine the possible involvement of these SNPs in cases of primary open-angle glaucoma (POAG) and primary angle-closure glaucoma...

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Source

Identifiers

PMID: 18223248
DOI: 10.1167/iovs.07-1557

Genes

LOXL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The LOXL1 gene variations are not associated with primary open-angle and primary angle-closure glaucomas.PMID 18223248Read ↗

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Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma.Semantic proximity Read ↗

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Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.Semantic proximity Read ↗

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