Article
Exfoliation syndrome and exfoliation glaucoma-associated LOXL1 variations are not involved in pigment dispersion syndrome and pigmentary glaucoma.
Molecular vision - 9 Jul 2008
Rao Kollu Nageswara, Ritch Robert, Dorairaj Syril K, Kaur Inderjeet, Liebmann Jeffrey M, Thomas Ravi, Chakrabarti Subhabrata
Abstract excerpt
PURPOSE: Single nucleotide polymorphisms (SNPs) in the LOXL1 gene have been implicated in exfoliation syndrome (XFS) and exfoliation glaucoma (XFG). We have shown that these SNPs are not associated with the primary glaucomas such as primary open-angle (POAG) glaucoma and primary angle-closure glaucoma (PACG). To further establish the specificity of LOXL1 SNPs for XFS and XFG, we determined whether these SNPs were...
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