Article
LOXL1 genetic polymorphisms are associated with exfoliation glaucoma in the Japanese population.
Molecular vision - 5 Jun 2008
Mori Kazuhiko, Imai Kojiro, Matsuda Akira, Ikeda Yoko, Naruse Shigeta, Hitora-Takeshita Hisako, Nakano Masakazu, Taniguchi Takazumi, Omi Natsue, Tashiro Kei, Kinoshita Shigeru
Abstract excerpt
PURPOSE: We performed genetic association studies using a native Japanese population to examine the reproducibility of results of lysyl oxidase-like 1 (LOXL1) genetic association studies for exfoliation glaucoma (XFG) beyond the differences of ethnicity. We also quantified LOXL1 mRNA expression in the human lens capsule to examine the possible correlation between LOXL1 expression and XFG pathogenesis. METHODS: We...
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