Article
Evaluation of LOXL1 polymorphisms in primary open-angle glaucoma in southern and northern Chinese.
Molecular vision - 1 Jan 2008
Gong Wei Fen, Chiang Sylvia W Y, Chen Li Jia, Tam Pancy O S, Jia Li Yun, Leung Dexter Y L, Geng Yi Qun, Tham Clement C Y, Lam Dennis S C, Ritch Robert, Wang Ningli, Pang Chi Pui
Abstract excerpt
PURPOSE: The lysyl oxidase-like protein 1 (LOXL1) gene is strongly associated with exfoliation glaucoma, which is very rare in the Chinese population. The implicated LOXL1 polymorphisms have not been associated with primary open-angle glaucoma (POAG). In this study, we investigated three of the LOXL1 polymorphisms in POAG in a southern Chinese population of Hong Kong and northern Chinese from Beijing. METHODS:...
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