Article

Distribution of rare <i>LOXL1</i> missense alleles, haplotypes and diplotypes suggests association with reduced risk of glaucoma-related exfoliation syndrome

2021-08-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> Common LOXL1 protein-altering variants are significant genetic risk factors for exfoliation syndrome (XFS) and the related secondary glaucoma (XFG). A rare LOXL1 missense allele has been associated with protective effects in a Japanese cohort, suggesting that other rare alleles may also exhibit protective effects. The goal of this study was to assess the contributions of rare LOX...

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Literature Corpus work: ffec8ba2-0ccd-514d-a823-6f35e0ab0392
DOI: 10.1101/2021.08.05.21261676

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Distribution of rare <i>LOXL1</i> missense alleles, haplotypes and diplotypes suggests association with reduced risk of glaucoma-related exfoliation syndromeDOI 10.1101/2021.08.05.21261676Read

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