Article
Lack of association between LOXL1 gene polymorphisms and primary open angle glaucoma in the Saudi Arabian population.
Ophthalmic genetics - 1 Sept 2012
Abu-Amero Khaled K, Osman Essam A, Azad Mohammad T, Allingham R Rand, Hauser Michael A, Al-Obeidan Saleh A
Abstract excerpt
PURPOSE: To investigate whether major single nucleotide polymorphisms (SNPs) in the LOXL1 gene associated with pseudoexfoliation glaucoma are associated with primary open angle glaucoma (POAG) in the Saudi Arabian population. METHODS: The regions of the LOXL1 gene associated with pseudoexfoliation glaucoma, encompassing the three common SNPs, (rs1048661, rs3825942 and rs2165241), were sequenced in a Saudi Arabian...
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