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Article

Altered Expression of Muscle‐ and Cytoskeleton‐Related Genes in a Rat Strain With Inherited Cryptorchidism

18 Apr 2008

Abstract excerpt

Development of the fetal gubernaculum is a prerequisite for testicular descent and dependent on insulin-like 3 and androgen, but knowledge of downstream effectors is limited. We analyzed transcript profiles in gubernaculum and testis to address changes occurring during normal and abnormal testicular descent in Long Evans wild-type (wt) and cryptorchid (orl) fetuses. Total RNA from male wt and orl gubernacula...

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PMID: 18222913
DOI: 10.2164/jandrol.107.003970

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Related research

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Research trail→

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Altered Expression of Muscle‐ and Cytoskeleton‐Related Genes in a Rat Strain With Inherited CryptorchidismPMID 18222913Read ↗

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Pathway analysis supports association of nonsyndromic cryptorchidism with genetic loci linked to cytoskeleton-dependent functions.Semantic proximity Read ↗

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Cryptorchidism in Mice with an Androgen Receptor Ablation in Gubernaculum TestisSemantic proximity Read ↗

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