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Article

Polygenic inheritance of cryptorchidism susceptibility in the LE/orl rat.

Molecular human reproduction - 1 Jan 2016

Barthold Julia Spencer, Pugarelli Joan, MacDonald Madolyn L, Ren Jia, Adetunji Modupeore O, Polson Shawn W, Mateson Abigail, Wang Yanping, Sol-Church Katia, McCahan Suzanne M, Akins Robert E, Devoto Marcella, Robbins Alan K

Abstract excerpt

STUDY HYPOTHESIS: Susceptibility to inherited cryptorchidism in the LE/orl rat may be associated with genetic loci that influence developmental patterning of the gubernaculum by the fetal testis. STUDY FINDING: Cryptorchidism in the LE/orl rat is associated with a unique combination of homozygous minor alleles at multiple loci, and the encoded proteins are co-localized with androgen receptor (AR) and Leydig cells...

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Identifiers

PMID: 26502805
DOI: 10.1093/molehr/gav060
PMCID: PMC4694052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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