Article
Channel glass-based detection of human short insertion/deletion polymorphisms by tandem hybridization.
Molecular biotechnology - 1 Feb 2008
Betanzos-Cabrera Gabriel, Harker Brent W, Doktycz Mitchel J, Weber James L, Beattie Kenneth L
Abstract excerpt
The development and critical evaluation of new technologies for identifying genetic polymorphisms will rapidly accelerate the discovery and diagnosis of disease-related genes. We report a novel way for distinguishing a new class of human DNA polymorphisms, short insertion/deletion polymorphisms (indels). A sensor with cylindrical pores named channel glass in combination with tandem hybridization, which uses a...
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