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Article

Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2008

Kereszturi Eva, Tarnok Zsanett, Bognar Emese, Lakatos Krisztina, Farkas Luca, Gadoros Julia, Sasvari-Szekely Maria, Nemoda Zsofia

Abstract excerpt

Methylphenidate is the most frequently prescribed drug in the treatment of attention deficit hyperactivity disorder (ADHD) but it is not effective in every case. Therefore, identifying genetic and/or biological markers predicting drug-response is increasingly important. Here we present a case-control study and pharmacogenetic association analyses in ADHD investigating three dopaminergic polymorphisms. Previous...

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Share to Attention Deficit Disorder with Hyperactivity
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Central Nervous System Stimulants

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Share to Dopamine Plasma Membrane Transport Proteins

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Share to Receptors, Dopamine D4

Source

Identifiers

PMID: 18214865
DOI: 10.1002/ajmg.b.30704

Genes

COMT
DRD4

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Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children.PMID 18214865Read ↗

Association of the catechol-O-methyltransferase polymorphism with methylphenidate response in a classroom setting in children with attention-deficit hyperactivity disorder.Semantic proximity Read ↗

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Cathechol-O-methyltransferase Val(158)Met polymorphism is associated with disruptive behavior disorders among children and adolescents with ADHD.Semantic proximity Read ↗

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