Article
Association analysis of norepinephrine transporter polymorphisms and methylphenidate response in ADHD patients.
Progress in neuro-psychopharmacology & biological psychiatry - 8 Jun 2018
Angyal Nora, Horvath Erzsebet Zsofia, Tarnok Zsanett, Richman Mara J, Bognar Emese, Lakatos Krisztina, Sasvari-Szekely Maria, Nemoda Zsofia
Abstract excerpt
AIMS: Methylphenidate (MPH) is the most frequently prescribed drug in Attention Deficit Hyperactivity Disorder (ADHD). Hitherto mostly the dopamine transporter gene has been studied in MPH-response and only a few studies analyzed the norepinephrine transporter (NET, SLC6A2) gene, although MPH is a potent inhibitor of both dopamine and norepinephrine transporters. We aimed to analyze this monoamine transporter...
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