Article
Participation of IIb-IIIa glycoprotein in spontaneous platelet aggregation.
Bulletin of experimental biology and medicine - 1 Apr 2007
Sirotkina O V, Zabotina A M, Taraskina A E, Sivachenko E B, Zueva E E, Kadinskaya M I, Buryachkovskaya L I, Uchitel' I A, Khaspekova S G, Vavilova T V, Shvartsman A L, Mazurov A V
Abstract excerpt
In some patients with stable and unstable angina pectoris and in some donors without clinical manifestations of cardiovascular diseases and other pathologies, spontaneous platelet aggregation was completely suppressed by glycoprotein IIb-IIIa antagonists blocking the interaction of this glycoprotein with fibrinogen. Antibodies inhibiting binding of glycoprotein Ib with von Willebrand factor had no effect on the...
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