Article
The impact of platelet glycoprotein IIIa and Ia polymorphisms in cardiovascular thrombotic disease.
Italian heart journal : official journal of the Italian Federation of Cardiology - 1 Jan 2003
Charakida Marietta, Tousoulis Dimitris, Stefanadis Christodoulos, Toutouzas Pavlos
Abstract excerpt
Platelet adhesion and aggregation play key roles in initiating coronary thrombosis and acute coronary syndromes. During the last decade platelet glycoprotein Ia and IIIa polymorphisms have been studied intensely in order to clarify their contribution to the thrombotic process and moreover their role in acute coronary syndromes. Studies examining these polymorphisms have been inconclusive and often controversial....
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