Article
Gene mutations of platelet glycoproteins and response to tirofiban in acute coronary syndrome.
Sao Paulo medical journal = Revista paulista de medicina - 19 Jan 2016
Mansur Antonio de Padua, Roggerio Alessandra, Takada Júlio Yoshio, Caribé Pérola Michelle Vasconcelos, Avakian Solange Desirée, Strunz Célia Maria Cassaro
Abstract excerpt
CONTEXT AND OBJECTIVES: Glycoprotein inhibitors (abciximab, eptifibatide and tirofiban) are used in patients with unstable angina and non-ST-segment elevation myocardial infarction before percutaneous coronary intervention. Of these, tirofiban is the least effective. We hypothesized that the response to tirofiban might be associated with glycoprotein gene mutations. DESIGN AND SETTING: Prospective study at...
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