Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene.

doi:10.1038/gene.2010.17

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Article

Elucidating the chromosome 9 association with AS; CARD9 is a candidate gene.

Genes and immunity - 1 Sept 2010

Pointon J J, Harvey D, Karaderi T, Appleton L H, Farrar C, Stone M A, Sturrock R D, Brown M A, Wordsworth B P

Abstract excerpt

Ankylosing spondylitis (AS) is polygenic with contributions from the immunologically relevant genes HLA-B*27, ERAP1 and IL23R. A recent genome-wide association screen (GWAS) identified associations (P approximately 0.005) with the non-synonymous single-nucleotide polymorphisms (nsSNPs), rs4077515 and rs3812571, in caspase recruitment domain-containing protein 9 (CARD9) and small nuclear RNA-activating complex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20463747
DOI: 10.1038/gene.2010.17
PMCID: PMC2933507

Genes

CARD9
ERAP1
SNAPC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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