Article
The SPINK gene family and celiac disease susceptibility.
Immunogenetics - 1 May 2007
Wapenaar Martin C, Monsuur Alienke J, Poell Jos, van 't Slot Ruben, Meijer Jos W R, Meijer Gerrit A, Mulder Chris J, Mearin Maria Luisa, Wijmenga Cisca
Abstract excerpt
The gene family of serine protease inhibitors of the Kazal type (SPINK) are functional and positional candidate genes for celiac disease (CD). Our aim was to assess the gut mucosal gene expression and genetic association of SPINK1, -2, -4, and -5 in the Dutch CD population. Gene expression was de...
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