Article
Identification of genetic variation and putative regulatory regions in bovine CARD15.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2006
Taylor Kristen H, Taylor Jeremy F, White Stephen N, Womack James E
Abstract excerpt
Mutations in caspase recruitment domain 15 (CARD15) are associated with susceptibility to Crohn's disease and Blau Syndrome. We performed comparative analyses of the bovine, murine, and human CARD15 transcripts to elucidate functionality of bovine CARD15 and examine its potential role in bovine disease resistance. Comparative analyses of intronic sequence across seven divergent species were performed to identify...
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