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Article

Drosophila abl and genetic redundancy in signal transduction.

Trends in genetics : TIG - 1 Jan 2000

Hoffmann F M

Abstract excerpt

Genetic studies on Drosophila Abl and, more recently, on mouse c-Abl and c-Src indicate that the functions of these non-receptor tyrosine kinases may duplicate activities of other molecules within signal transduction pathways. In Drosophila, second-site mutations have been recovered that disrupt...

Topics

Alleles
Animals
Cytoplasm
Drosophila melanogaster
Embryo, Nonmammalian
Embryonic Development
Embryonic and Fetal Development
Enzyme Induction
Genes, Lethal
Genes, abl
Models, Genetic
Mutation
Protein Processing, Post-Translational

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein-Tyrosine Kinases

Proto-Oncogene Proteins c-abl

Signal Transduction

Source

Identifiers

PMID: 1820686
DOI: 10.1016/0168-9525(91)90254-f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1820686-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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