Article
The promiscuous role of the epsilon subunit in GABAA receptor biogenesis.
Molecular and cellular neurosciences - 1 Mar 2008
Bollan Karen A, Baur Roland, Hales Tim G, Sigel Erwin, Connolly Christopher N
Abstract excerpt
The formation of alpha1beta2gamma2epsilon receptors suggests that the epsilon subunit does not displace the single gamma2 subunit in alpha1beta2gamma2 receptors. Thus, epsilon must replace alpha and/or beta subunit(s) if the pentameric receptor structure is to be preserved. To assess the potential for which subunit is replaced in alphabetaepsilon and alphabetagammaepsilon receptors we analyzed the assembly and...
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