Article
Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells.
American journal of physiology. Heart and circulatory physiology - 1 Mar 2008
Patschan Susann, Chen Jun, Polotskaia Alla, Mendelev Natalja, Cheng Jennifer, Patschan Daniel, Goligorsky Michael S
Abstract excerpt
Our group (Patschan S, Chen J, Gealekman O, Krupincza K, Wang M, Shu L, Shayman JA, Goligorsky MS; Am J Physiol Renal Physiol 294: F100-F109, 2008) previously observed an accumulation of gangliosides coincident with development of cell senescence and demonstrated lysosomal permeabilization in human umbilical vein endothelial cells exposed to glycated collagen I (GC). Therefore, we investigated whether the...
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