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Autophagy in homocysteine‑induced HUVEC senescence

31 May 2023

Abstract excerpt

The senescence of vascular endothelial cells (VECs) drives the occurrence and development of cardiovascular disease (CVD). Homocysteine (HCY) is a general risk factor for age-associated CVDs. Autophagy, an evolutionarily conserved lysosomal protein degradation pathway, serves a part in VEC senescence. The purpose of this study was to investigate the role of autophagy in HCY-induced endothelial cell senescence and...

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PMID: 37324509
DOI: 10.3892/etm.2023.12053

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