Article
Distribution of CYP1A1*2A polymorphism in adult patients with acute lymphoblastic leukemia in a Mexican population.
Blood cells, molecules & diseases - 1 Jan 2000
Gallegos-Arreola M P, González-García J R, Figuera L E, Puebla-Pérez A M, Delgado-Lamas J L, Zúñiga-González G M
Abstract excerpt
The effects of the CYP1A1*2A genotype on susceptibility to leukemia have received particular attention in recent years because this enzyme plays a central role in the activation of carcinogens. Several polymorphisms at the CYP1A1 locus have been identified and their genotypes appear to exhibit population frequencies that depend on ethnicity. We evaluated the role of the CYP1A1*2A genotype in adults with acute...
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