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Functional association between the Helicobacter pylori virulence factors VacA and CagA

17 Jan 2008

Abstract excerpt

The Helicobacter pylori virulence factors CagA and VacA are implicated in the development of gastroduodenal diseases. Most strains possessing CagA also possess the more virulent vacuolating form of VacA. This study assessed the significance of possession of both virulence factors in terms of their effect on gastric epithelial cells, using a set of minimally passaged, isogenic VacA, CagA and CagE mutants in H....

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PMID: 18201978
DOI: 10.1099/jmm.0.47465-0

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