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Article

Virulence Factors of <i>Helicobacter pylori</i> Responsible for Gastric Diseases in Mongolian Gerbil

4 Dec 2000

Abstract excerpt

Helicobacter pylori infection induces various gastroduodenal diseases. We examined the role of two genes, vacA and cagE, in the gastric pathogenesis induced by H. pylori using a long-term (62 wk) animal model. Reportedly, both genes are associated with the virulence of H. pylori: vacA encodes vacuolating cytotoxin, and cagE, with other genes in the cag pathogenicity islands, encodes a type IV secretion system....

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Identifiers

PMID: 11104802
DOI: 10.1084/jem.192.11.1601

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