Article
Leukoreduction of blood transfusions does not diminish transfusion-associated microchimerism in trauma patients.
Transfusion - 1 Nov 2006
Utter Garth H, Nathens Avery B, Lee Tzong-Hae, Reed William F, Owings John T, Nester Theresa A, Busch Michael P
Abstract excerpt
BACKGROUND: Transfusion of trauma patients can result in long-term survival of donor white blood cells (WBCs) or "transfusion-associated microchimerism" (TA-MC). The aim was to determine whether leukoreduction of blood transfusions, advocated to reduce the immunomodulatory effect of transfusion, decreases the likelihood of developing TA-MC. STUDY DESIGN AND METHODS: A subgroup of trauma patients from a randomized...
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